2019

 

  1. Vitamin D release across abdominal adipose tissue in lean and obese men: The effect of ß-adrenergic stimulation.

Pramono A, Jocken JWE, Goossens GH, Blaak EE.

Physiol Rep. 2019 Dec;7(24):e14308. doi: 10.14814/phy2.14308. PMID: 31872972 Free PMC article.

 

  1. Distal colonic transit is linked to gut microbiota diversity and microbial fermentation in humans with slow colonic transit.

Müller M, Hermes GDA, Canfora EE, Smidt H, Masclee AAM, Zoetendal EG, Blaak EE.

Am J Physiol Gastrointest Liver Physiol. 2020 Feb 1;318(2):G361-G369. doi: 10.1152/ajpgi.00283.2019. Epub 2019 Dec 23. PMID: 31869241 Free article.

 

  1. Short-term bed rest-induced insulin resistance cannot be explained by increased mitochondrial H2 O2

Dirks ML, Miotto PM, Goossens GH, Senden JM, Petrick HL, van Kranenburg J, van Loon LJC, Holloway GP.

J Physiol. 2020 Jan;598(1):123-137. doi: 10.1113/JP278920. Epub 2019 Dec 26. PMID: 31721213 Free article.

 

  1. Plasma cathepsin D activity is negatively associated with hepatic insulin sensitivity in overweight and obese humans.

Ding L, Goossens GH, Oligschlaeger Y, Houben T, Blaak EE, Shiri-Sverdlov R.

Diabetologia. 2020 Feb;63(2):374-384. doi: 10.1007/s00125-019-05025-2. Epub 2019 Nov 5. PMID: 31690989 Free PMC article.

 

  1. Subcutaneous Adipose Tissue and Systemic Inflammation Are Associated With Peripheral but Not Hepatic Insulin Resistance in Humans.

van der Kolk BW, Kalafati M, Adriaens M, van Greevenbroek MMJ, Vogelzangs N, Saris WHM, Astrup A, Valsesia A, Langin D, van der Kallen CJH, Eussen SJPM, Schalkwijk CG, Stehouwer CDA, Goossens GH, Arts ICW, Jocken JWE, Evelo CT, Blaak EE.

Diabetes. 2019 Dec;68(12):2247-2258. doi: 10.2337/db19-0560. Epub 2019 Sep 6. PMID: 31492661 Free article. Clinical Trial.

 

  1. Circulating but not faecal short-chain fatty acids are related to insulin sensitivity, lipolysis and GLP-1 concentrations in humans.

Müller M, Hernández MAG, Goossens GH, Reijnders D, Holst JJ, Jocken JWE, van Eijk H, Canfora EE, Blaak EE.

Sci Rep. 2019 Aug 29;9(1):12515. doi: 10.1038/s41598-019-48775-0. PMID: 31467327 Free PMC article.

 

  1. The Short-Chain Fatty Acid Acetate in Body Weight Control and Insulin Sensitivity.

Hernández MAG, Canfora EE, Jocken JWE, Blaak EE.

Nutrients. 2019 Aug 18;11(8):1943. doi: 10.3390/nu11081943. PMID: 31426593 Free PMC article. Review.

 

  1. Improved quantification of muscle insulin sensitivity using oral glucose tolerance test data: the MISI Calculator.

O'Donovan SD, Lenz M, Goossens GH, van der Kallen CJH, Eussen SJMP, Stehouwer CDA, van Greevenbroek MM, Schram MT, Sep SJ, Peeters RLM, Blaak EE, van Riel NAW, de Kok TMCM, Arts ICW.

Sci Rep. 2019 Jun 28;9(1):9388. doi: 10.1038/s41598-019-45858-w. PMID: 31253846 Free PMC article.

 

  1. Lipotoxicity plays a key role in the development of both insulin resistance and muscle atrophy in patients with type 2 diabetes.

Meex RCR, Blaak EE, van Loon LJC.

Obes Rev. 2019 Sep;20(9):1205-1217. doi: 10.1111/obr.12862. Epub 2019 Jun 26. PMID: 31240819 Free PMC article. Review.

 

  1. Blood flow restricted resistance exercise and reductions in oxygen tension attenuate mitochondrial H2 O2 emission rates in human skeletal muscle.

Petrick HL, Pignanelli C, Barbeau PA, Churchward-Venne TA, Dennis KMJH, van Loon LJC, Burr JF, Goossens GH, Holloway GP. J Physiol. 2019 Aug;597(15):3985-3997. doi: 10.1113/JP277765. Epub 2019 Jul 7. PMID: 31194254 Free article.

 

  1. The Impact of Dairy Products in the Development of Type 2 Diabetes: Where Does the Evidence Stand in 2019?

Guo J, Givens DI, Astrup A, Bakker SJL, Goossens GH, Kratz M, Marette A, Pijl H, Soedamah-Muthu SS.

Adv Nutr. 2019 Nov 1;10(6):1066-1075. doi: 10.1093/advances/nmz050. PMID: 31124561 Free PMC article. Review.

 

  1. Oxygenation of adipose tissue: A human perspective.

Lempesis IG, van Meijel RLJ, Manolopoulos KN, Goossens GH.

Acta Physiol (Oxf). 2020 Jan;228(1):e13298. doi: 10.1111/apha.13298. Epub 2019 Jun 2. PMID: 31077538 Free PMC article. Review.

 

  1. Effects of dietary fat on insulin secretion in subjects with the metabolic syndrome.

Gulseth HL, Gjelstad IMF, Tiereny AC, McCarthy D, Lovegrove JA, Defoort C, Blaak EE, Lopez-Miranda J, Dembinska-Kiec A, Risérus U, Roche HM, Drevon CA, Birkeland KI.

Eur J Endocrinol. 2019 May 1;180(5):321-328. doi: 10.1530/EJE-19-0022. PMID: 30893645 Clinical Trial.

 

  1. A comparison between the abdominal and femoral adipose tissue proteome of overweight and obese women.

Vogel MAA, Wang P, Bouwman FG, Hoebers N, Blaak EE, Renes J, Mariman EC, Goossens GH.

Sci Rep. 2019 Mar 12;9(1):4202. doi: 10.1038/s41598-019-40992-x. PMID: 30862933 Free PMC article. Clinical Trial.

 

  1. The ABCD of Obesity: An EASO Position Statement on a Diagnostic Term with Clinical and Scientific Implications.

Frühbeck G, Busetto L, Dicker D, Yumuk V, Goossens GH, Hebebrand J, Halford JGC, Farpour-Lambert NJ, Blaak EE, Woodward E, Toplak H.

Obes Facts. 2019;12(2):131-136. doi: 10.1159/000497124. Epub 2019 Mar 7. PMID: 30844811 Free PMC article.

 

  1. An integrative systems genetic analysis of mammalian lipid metabolism.

Parker BL, Calkin AC, Seldin MM, Keating MF, Tarling EJ, Yang P, Moody SC, Liu Y, Zerenturk EJ, Needham EJ, Miller ML, Clifford BL, Morand P, Watt MJ, Meex RCR, Peng KY, Lee R, Jayawardana K, Pan C, Mellett NA, Weir JM, Lazarus R, Lusis AJ, Meikle PJ, James DE, de Aguiar Vallim TQ, Drew BG.

Nature. 2019 Mar;567(7747):187-193. doi: 10.1038/s41586-019-0984-y. Epub 2019 Feb 27. PMID: 30814737 Free PMC article.

 

  1. Vitamin D deficiency in the aetiology of obesity-related insulin resistance.

Pramono A, Jocken JWE, Blaak EE.

Diabetes Metab Res Rev. 2019 Jul;35(5):e3146. doi: 10.1002/dmrr.3146. Epub 2019 Mar 18. PMID: 30801902 Review.

 

  1. Gut microbial metabolites in obesity, NAFLD and T2DM.

Canfora EE, Meex RCR, Venema K, Blaak EE.

Nat Rev Endocrinol. 2019 May;15(5):261-273. doi: 10.1038/s41574-019-0156-z. PMID: 30670819 Review.

 

  1. Perilipin 5 Deletion in Hepatocytes Remodels Lipid Metabolism and Causes Hepatic Insulin Resistance in Mice.

Keenan SN, Meex RC, Lo JCY, Ryan A, Nie S, Montgomery MK, Watt MJ.

Diabetes. 2019 Mar;68(3):543-555. doi: 10.2337/db18-0670. Epub 2019 Jan 7. PMID: 30617219

 

  1. Impact of early events and lifestyle on the gut microbiota and metabolic phenotypes in young school-age children.

Zhong H, Penders J, Shi Z, Ren H, Cai K, Fang C, Ding Q, Thijs C, Blaak EE, Stehouwer CDA, Xu X, Yang H, Wang J, Wang J, Jonkers DMAE, Masclee AAM, Brix S, Li J, Arts ICW, Kristiansen K.

Microbiome. 2019 Jan 4;7(1):2. doi: 10.1186/s40168-018-0608-z. PMID: 30609941 Free PMC article.

 

  1. Plasma lipid profiling of tissue-specific insulin resistance in human obesity.

van der Kolk BW, Vogelzangs N, Jocken JWE, Valsesia A, Hankemeier T, Astrup A, Saris WHM, Arts ICW, van Greevenbroek MMJ, Blaak EE; DiOGenes consortium.

Int J Obes (Lond). 2019 May;43(5):989-998. doi: 10.1038/s41366-018-0189-8. Epub 2018 Sep 21. PMID: 30242234 Clinical Trial.

 

  1. Vitamin D and Tissue-Specific Insulin Sensitivity in Humans With Overweight/Obesity.

Pramono A, Jocken JWE, Essers YPG, Goossens GH, Blaak EE.

J Clin Endocrinol Metab. 2019 Jan 1;104(1):49-56. doi: 10.1210/jc.2018-00995. PMID: 30137362

 

  1. Distal versus proximal intestinal short-chain fatty acid release in man.

Neis EP, van Eijk HM, Lenaerts K, Olde Damink SW, Blaak EE, Dejong CH, Rensen SS.

Gut. 2019 Apr;68(4):764-765. doi: 10.1136/gutjnl-2018-316161. Epub 2018 Apr 4. PMID: 29618497 No abstract available.