1 The Effects of Mild Intermittent Hypoxia Exposure on the Abdominal Subcutaneous Adipose Tissue Proteome in Overweight and Obese Men: A First-in-Human Randomized, Single-Blind, and Cross-Over Study.

Van Meijel RLJ, Wang P, Bouwman F, Blaak EE, Mariman ECM, Goossens GH.

Front Physiol. 2022 Jan 4;12:791588. doi: 10.3389/fphys.2021.791588. eCollection 2021. PMID: 35058800 Free PMC article.

 

2 Health Effects of Increasing Protein Intake Above the Current Population Reference Intake in Older Adults: A Systematic Review of the Health Council of the Netherlands.

Hengeveld LM, de Goede J, Afman LA, Bakker SJL, Beulens JWJ, Blaak EE, Boersma E, Geleijnse JM, van Goudoever JHB, Hopman MTE, Iestra JA, Kremers SPJ, Mensink RP, de Roos NM, Stehouwer CDA, Verkaik-Kloosterman J, de Vet E, Visser M.

Adv Nutr. 2021 Nov 23:nmab140. doi: 10.1093/advances/nmab140. Online ahead of print. PMID: 35016214

 

3 The association of changes in body mass index and metabolic parameters between adults with overweight or obesity and their children in a family-based randomized trial (DiOGenes).

Pang MD, Yilmaz H, Astrup A, Blaak EE, van Baak MA.

Pediatr Obes. 2021 Dec 30:e12884. doi: 10.1111/ijpo.12884. Online ahead of print. PMID: 34970862

 

4 Ovarian cancer ascites induces skeletal muscle wasting in vitro and reflects sarcopenia in patients.

Ubachs J, van de Worp WRPH, Vaes RDW, Pasmans K, Langen RC, Meex RCR, van Bijnen AAJHM, Lambrechts S, Van Gorp T, Kruitwagen RFPM, Olde Damink SWM, Rensen SS.

J Cachexia Sarcopenia Muscle. 2022 Feb;13(1):311-324. doi: 10.1002/jcsm.12885. Epub 2021 Dec 23. PMID: 34951138 Free PMC article.

 

5 An interferon-related signature characterizes the whole blood transcriptome profile of insulin-resistant individuals-the CODAM study.

Kalafati M, Kutmon M, Evelo CT, van der Kallen CJH, Schalkwijk CG, Stehouwer CDA, Consortium BIOS, Blaak EE, van Greevenbroek MMJ, Adriaens M.

Genes Nutr. 2021 Dec 9;16(1):22. doi: 10.1186/s12263-021-00702-7. PMID: 34886800

 

6 Hepatic Steatosis Contributes to the Development of Muscle Atrophy via Inter-Organ Crosstalk.

Pasmans K, Adriaens ME, Olinga P, Langen R, Rensen SS, Schaap FG, Olde Damink SWM, Caiment F, van Loon LJC, Blaak EE, Meex RCR.

Front Endocrinol (Lausanne). 2021 Oct 11;12:733625. doi: 10.3389/fendo.2021.733625. eCollection 2021. PMID: 34707570 Free PMC article.

 

7 L-arabinose co-ingestion delays glucose absorption derived from sucrose in healthy men and women: a double-blind, randomised crossover trial.

Pasmans K, Meex RCR, Trommelen J, Senden JMG, Vaughan EE, van Loon LJC, Blaak EE.

Br J Nutr. 2021 Oct 18:1-10. doi: 10.1017/S0007114521004153. Online ahead of print. PMID: 34657640

 

8 Physical activity and fat-free mass during growth and in later life.

Westerterp KR, Yamada Y, Sagayama H, Ainslie PN, Andersen LF, Anderson LJ, Arab L, Baddou I, Bedu-Addo K, Blaak EE, Blanc S, Bonomi AG, Bouten CVC, Bovet P, Buchowski MS, Butte NF, Camps SGJA, Close GL, Cooper JA, Das SK, Cooper R, Dugas LR, Ekelund U, Entringer S, Forrester T, Fudge BW, Goris AH, Gurven M, Hambly C, El Hamdouchi A, Hoos MB, Hu S, Joonas N, Joosen AM, Katzmarzyk P, Kempen KP, Kimura M, Kraus WE, Kushner RF, Lambert EV, Leonard WR, Lessan N, Martin CK, Medin AC, Meijer EP, Morehen JC, Morton JP, Neuhouser ML, Nicklas TA, Ojiambo RM, Pietiläinen KH, Pitsiladis YP, Plange-Rhule J, Plasqui G, Prentice RL, Rabinovich RA, Racette SB, Raichlen DA, Ravussin E, Reynolds RM, Roberts SB, Schuit AJ, Sjödin AM, Stice E, Urlacher SS, Valenti G, Van Etten LM, Van Mil EA, Wells JCK, Wilson G, Wood BM, Yanovski J, Yoshida T, Zhang X, Murphy-Alford AJ, Loechl CU, Luke AH, Pontzer H, Rood J, Schoeller DA, Wong WW, Speakman JR; International Atomic Energy Agency Doubly Labeled Water database group.

Am J Clin Nutr. 2021 Nov 8;114(5):1583-1589. doi: 10.1093/ajcn/nqab260. PMID: 34477824 Free PMC article.

 

9 Energy compensation and adiposity in humans.

Careau V, Halsey LG, Pontzer H, Ainslie PN, Andersen LF, Anderson LJ, Arab L, Baddou I, Bedu-Addo K, Blaak EE, Blanc S, Bonomi AG, Bouten CVC, Buchowski MS, Butte NF, Camps SGJA, Close GL, Cooper JA, Das SK, Cooper R, Dugas LR, Eaton SD, Ekelund U, Entringer S, Forrester T, Fudge BW, Goris AH, Gurven M, Hambly C, El Hamdouchi A, Hoos MB, Hu S, Joonas N, Joosen AM, Katzmarzyk P, Kempen KP, Kimura M, Kraus WE, Kushner RF, Lambert EV, Leonard WR, Lessan N, Martin CK, Medin AC, Meijer EP, Morehen JC, Morton JP, Neuhouser ML, Nicklas TA, Ojiambo RM, Pietiläinen KH, Pitsiladis YP, Plange-Rhule J, Plasqui G, Prentice RL, Rabinovich RA, Racette SB, Raichlen DA, Ravussin E, Reilly JJ, Reynolds RM, Roberts SB, Schuit AJ, Sjödin AM, Stice E, Urlacher SS, Valenti G, Van Etten LM, Van Mil EA, Wells JCK, Wilson G, Wood BM, Yanovski J, Yoshida T, Zhang X, Murphy-Alford AJ, Loechl CU, Luke AH, Rood J, Sagayama H, Schoeller DA, Wong WW, Yamada Y, Speakman JR; IAEA DLW database group.

Curr Biol. 2021 Oct 25;31(20):4659-4666.e2. doi: 10.1016/j.cub.2021.08.016. Epub 2021 Aug 27. PMID: 34453886 Free PMC article.

 

10 The triglyceride-glucose index as an adiposity marker and a predictor of fat loss induced by a low-calorie diet.

Vidal-Ostos F, Ramos-Lopez O, Blaak EE, Astrup A, Martinez JA.

Eur J Clin Invest. 2022 Jan;52(1):e13674. doi: 10.1111/eci.13674. Epub 2021 Sep 5. PMID: 34453322

 

11 Resveratrol supplementation reduces ACE2 expression in human adipose tissue.

de Ligt M, Hesselink MKC, Jorgensen J, Hoebers N, Blaak EE, Goossens GH.

Adipocyte. 2021 Dec;10(1):408-411. doi: 10.1080/21623945.2021.1965315. PMID: 34402717 Free PMC article. Clinical Trial.

 

12 Daily energy expenditure through the human life course.

Pontzer H, Yamada Y, Sagayama H, Ainslie PN, Andersen LF, Anderson LJ, Arab L, Baddou I, Bedu-Addo K, Blaak EE, Blanc S, Bonomi AG, Bouten CVC, Bovet P, Buchowski MS, Butte NF, Camps SG, Close GL, Cooper JA, Cooper R, Das SK, Dugas LR, Ekelund U, Entringer S, Forrester T, Fudge BW, Goris AH, Gurven M, Hambly C, El Hamdouchi A, Hoos MB, Hu S, Joonas N, Joosen AM, Katzmarzyk P, Kempen KP, Kimura M, Kraus WE, Kushner RF, Lambert EV, Leonard WR, Lessan N, Martin C, Medin AC, Meijer EP, Morehen JC, Morton JP, Neuhouser ML, Nicklas TA, Ojiambo RM, Pietiläinen KH, Pitsiladis YP, Plange-Rhule J, Plasqui G, Prentice RL, Rabinovich RA, Racette SB, Raichlen DA, Ravussin E, Reynolds RM, Roberts SB, Schuit AJ, Sjödin AM, Stice E, Urlacher SS, Valenti G, Van Etten LM, Van Mil EA, Wells JCK, Wilson G, Wood BM, Yanovski J, Yoshida T, Zhang X, Murphy-Alford AJ, Loechl C, Luke AH, Rood J, Schoeller DA, Westerterp KR, Wong WW, Speakman JR; IAEA DLW

Database Consortium. Science. 2021 Aug 13;373(6556):808-812. doi: 10.1126/science.abe5017. PMID: 34385400

 

13 Neprilysin Inhibition Increases Glucagon Levels in Humans and Mice With Potential Effects on Amino Acid Metabolism.

Kjeldsen SAS, Hansen LH, Esser N, Mongovin S, Winther-Sørensen M, Galsgaard KD, Hunt JE, Kissow H, Ceutz FR, Terzic D, Mark PD, Plomgaard P, Goetze JP, Goossens GH, Blaak EE, Deacon CF, Rosenkilde MM, Zraika S, Holst JJ, Wewer Albrechtsen NJ.

J Endocr Soc. 2021 May 16;5(9):bvab084. doi: 10.1210/jendso/bvab084. eCollection 2021 Sep 1. PMID: 34337276 Free PMC article.

 

14 The PERSonalized Glucose Optimization Through Nutritional Intervention (PERSON) Study: Rationale, Design and Preliminary Screening Results.

Gijbels A, Trouwborst I, Jardon KM, Hul GB, Siebelink E, Bowser SM, Yildiz D, Wanders L, Erdos B, Thijssen DHJ, Feskens EJM, Goossens GH, Afman LA, Blaak EE.

Front Nutr. 2021 Jun 30;8:694568. doi: 10.3389/fnut.2021.694568. eCollection 2021. PMID: 34277687 Free PMC article.

 

15 Abdominal and gluteofemoral fat depots show opposing associations with postprandial lipemia.

Christiansen MR, Ureña MG, Borisevich D, Grarup N, Martínez JA, Oppert JM, Sørensen TI, Hansen T, Blaak EE, Kilpeläinen TO.

Am J Clin Nutr. 2021 Oct 4;114(4):1467-1475. doi: 10.1093/ajcn/nqab219. PMID: 34254976

 

16 Mild intermittent hypoxia exposure induces metabolic and molecular adaptations in men with obesity.

van Meijel RLJ, Vogel MAA, Jocken JWE, Vliex LMM, Smeets JSJ, Hoebers N, Hoeks J, Essers Y, Schoffelen PFM, Sell H, Kersten S, M A Rouschop K, Blaak EE, Goossens GH.

Mol Metab. 2021 Nov;53:101287. doi: 10.1016/j.molmet.2021.101287. Epub 2021 Jul 3. PMID: 34224918 Free PMC article.

 

17 Acetate Does Not Affect Palmitate Oxidation and AMPK Phosphorylation in Human Primary Skeletal Muscle Cells.

González Hernández MA, Blaak EE, Hoebers NTH, Essers YPG, Canfora EE, Jocken JWE.

Front Endocrinol (Lausanne). 2021 Jun 17;12:659928. doi: 10.3389/fendo.2021.659928. eCollection 2021. PMID: 34220709 Free PMC article.

 

18 Assessing the Contribution of Relative Macrophage Frequencies to Subcutaneous Adipose Tissue.

Kalafati M, Lenz M, Ertaylan G, Arts ICW, Evelo CT, van Greevenbroek MMJ, Blaak EE, Adriaens M, Kutmon M.

Front Nutr. 2021 May 31;8:675935. doi: 10.3389/fnut.2021.675935. eCollection 2021. PMID: 34136521 Free PMC article.

 

19 Sexual Dimorphism in Body Weight Loss, Improvements in Cardiometabolic Risk Factors and Maintenance of Beneficial Effects 6 Months after a Low-Calorie Diet: Results from the Randomized Controlled DiOGenes Trial.

Trouwborst I, Goossens GH, Astrup A, Saris WHM, Blaak EE.

Nutrients. 2021 May 10;13(5):1588. doi: 10.3390/nu13051588. PMID: 34068687 Free PMC article. Clinical Trial.

 

20 The angiotensin II type 1 receptor blocker valsartan in the battle against COVID-19.

de Ligt M, Hesselink MKC, Jorgensen J, Jocken JWE, Blaak EE, Goossens GH.

Obesity (Silver Spring). 2021 Sep;29(9):1423-1426. doi: 10.1002/oby.23221. Epub 2021 Aug 2. PMID: 33955183 Free PMC article. Clinical Trial.

 

21 Vaccinating People with Obesity for COVID-19: EASO Call for Action.

Dicker D, Golan R, Baker JL, Busetto L, Frühbeck G, Goossens GH, Halford JCG, Holm JC, Woodward E, Farpour-Lambert NJ.

Obes Facts. 2021;14(3):334-335. doi: 10.1159/000516524. Epub 2021 Apr 29. PMID: 33915546 Free PMC article. No abstract available.

 

22 Faecal microbial metabolites of proteolytic and saccharolytic fermentation in relation to degree of insulin resistance in adult individuals.

Hernández MAG, Canfora EE, Blaak EE.

Benef Microbes. 2021 Jun 15;12(3):259-266. doi: 10.3920/BM2020.0179. Epub 2021 Apr 21. PMID: 33880973

 

23 The impact of hypoxia exposure on glucose homeostasis in metabolically compromised humans: A systematic review.

van Hulten V, van Meijel RLJ, Goossens GH.

Rev Endocr Metab Disord. 2021 Jun;22(2):471-483. doi: 10.1007/s11154-021-09654-0. Epub 2021 Apr 14. PMID: 33851320 Free PMC article. Review.

 

24 Editorial: Personalized Nutrition.

Blaak EE, Roche HM, Afman LA.

Front Nutr. 2021 Mar 25;8:669307. doi: 10.3389/fnut.2021.669307. eCollection 2021. PMID: 33842527 Free PMC article. No abstract available.

 

25 Carbohydrates: Separating fact from fiction.

Blaak EE, Riccardi G, Cho L.

Atherosclerosis. 2021 Jul;328:114-123. doi: 10.1016/j.atherosclerosis.2021.03.025. Epub 2021 Mar 28. PMID: 33832770 Review.

 

26 Personalized computational model quantifies heterogeneity in postprandial responses to oral glucose challenge.

Erdős B, van Sloun B, Adriaens ME, O'Donovan SD, Langin D, Astrup A, Blaak EE, Arts ICW, van Riel NAW.

PLoS Comput Biol. 2021 Mar 31;17(3):e1008852. doi: 10.1371/journal.pcbi.1008852. eCollection 2021 Mar. PMID: 33788828 Free PMC article.

 

27 The air that we (do not) breathe: lower adipose tissue oxygen availability in patients with obesity hypoventilation syndrome?

Goossens GH.

Int J Obes (Lond). 2021 Jun;45(6):1161-1162. doi: 10.1038/s41366-021-00797-3. Epub 2021 Mar 23. PMID: 33758340 No abstract available.

 

28 A standard calculation methodology for human doubly labeled water studies.

Speakman JR, Yamada Y, Sagayama H, Berman ESF, Ainslie PN, Andersen LF, Anderson LJ, Arab L, Baddou I, Bedu-Addo K, Blaak EE, Blanc S, Bonomi AG, Bouten CVC, Bovet P, Buchowski MS, Butte NF, Camps SGJA, Close GL, Cooper JA, Creasy SA, Das SK, Cooper R, Dugas LR, Ebbeling CB, Ekelund U, Entringer S, Forrester T, Fudge BW, Goris AH, Gurven M, Hambly C, El Hamdouchi A, Hoos MB, Hu S, Joonas N, Joosen AM, Katzmarzyk P, Kempen KP, Kimura M, Kraus WE, Kushner RF, Lambert EV, Leonard WR, Lessan N, Ludwig DS, Martin CK, Medin AC, Meijer EP, Morehen JC, Morton JP, Neuhouser ML, Nicklas TA, Ojiambo RM, Pietiläinen KH, Pitsiladis YP, Plange-Rhule J, Plasqui G, Prentice RL, Rabinovich RA, Racette SB, Raichlen DA, Ravussin E, Reynolds RM, Roberts SB, Schuit AJ, Sjödin AM, Stice E, Urlacher SS, Valenti G, Van Etten LM, Van Mil EA, Wells JCK, Wilson G, Wood BM, Yanovski J, Yoshida T, Zhang X, Murphy-Alford AJ, Loechl CU, Melanson EL, Luke AH, Pontzer H, Rood J, Schoeller DA, Westerterp KR, Wong WW; IAEA DLW database group.

Cell Rep Med. 2021 Feb 16;2(2):100203. doi: 10.1016/j.xcrm.2021.100203. eCollection 2021 Feb 16. PMID: 33665639 Free PMC article.

 

29 Goals in Nutrition Science 2020-2025.

Bassaganya-Riera J, Berry EM, Blaak EE, Burlingame B, le Coutre J, van Eden W, El-Sohemy A, German JB, Knorr D, Lacroix C, Muscaritoli M, Nieman DC, Rychlik M, Scholey A, Serafini M.

Front Nutr. 2021 Feb 9;7:606378. doi: 10.3389/fnut.2020.606378. eCollection 2020. PMID: 33665201 Free PMC article. Review.

 

30 Effects of alpha-glucosidase-inhibiting drugs on acute postprandial glucose and insulin responses: a systematic review and meta-analysis.

Alssema M, Ruijgrok C, Blaak EE, Egli L, Dussort P, Vinoy S, Dekker JM, Denise Robertson M.

Nutr Diabetes. 2021 Mar 3;11(1):11. doi: 10.1038/s41387-021-00152-5. PMID: 33658478 Free PMC article.

 

31 Measurement of human abdominal and femoral intravascular adipose tissue blood flow using percutaneous Doppler ultrasound.

Lempesis IG, Goossens GH, Manolopoulos KN.

Adipocyte. 2021 Dec;10(1):119-123. doi: 10.1080/21623945.2021.1888471. PMID: 33591224 Free PMC article.

 

32 Differential Mitochondrial Gene Expression in Adipose Tissue Following Weight Loss Induced by Diet or Bariatric Surgery.

van der Kolk BW, Muniandy M, Kaminska D, Alvarez M, Ko A, Miao Z, Valsesia A, Langin D, Vaittinen M, Pääkkönen M, Jokinen R, Kaye S, Heinonen S, Virtanen KA, Andersson DP, Männistö V, Saris WH, Astrup A, Rydén M, Blaak EE, Pajukanta P, Pihlajamäki J, Pietiläinen KH.

J Clin Endocrinol Metab. 2021 Apr 23;106(5):1312-1324. doi: 10.1210/clinem/dgab072. PMID: 33560372 Free PMC article.

 

33 The Impact of Artificial Sweeteners on Body Weight Control and Glucose Homeostasis.

Pang MD, Goossens GH, Blaak EE. Front Nutr. 2021 Jan 7;7:598340. doi: 10.3389/fnut.2020.598340. eCollection 2020. PMID: 33490098 Free PMC article. Review.

 

34 The association between vitamin D receptor polymorphisms and tissue-specific insulin resistance in human obesity.

Pramono A, Jocken JWE, Adriaens ME, Hjorth MF, Astrup A, Saris WHM, Blaak EE.

Int J Obes (Lond). 2021 Apr;45(4):818-827. doi: 10.1038/s41366-021-00744-2. Epub 2021 Jan 20. PMID: 33473175

 

35 Sexual dimorphism in cardiometabolic health: the role of adipose tissue, muscle and liver.

Goossens GH, Jocken JWE, Blaak EE.

Nat Rev Endocrinol. 2021 Jan;17(1):47-66. doi: 10.1038/s41574-020-00431-8. Epub 2020 Nov 10. PMID: 33173188 Review.

 

36 Gut microbiome stability and resilience: elucidating the response to perturbations in order to modulate gut health.

Fassarella M, Blaak EE, Penders J, Nauta A, Smidt H, Zoetendal EG.

Gut. 2021 Mar;70(3):595-605. doi: 10.1136/gutjnl-2020-321747. Epub 2020 Oct 13. PMID: 33051190 Review.

 

37 Mitochondrial Dysfunction is a Key Pathway that Links Saturated Fat Intake to the Development and Progression of NAFLD.

Meex RCR, Blaak EE.

Mol Nutr Food Res. 2021 Jan;65(1):e1900942. doi: 10.1002/mnfr.201900942. Epub 2020 Jul 13. PMID: 32574416 Free PMC article. Review.

 

38 Reducing postprandial glucose in dietary intervention studies and the magnitude of the effect on diabetes-related risk factors: a systematic review and meta-analysis.

Ruijgrok C, Blaak EE, Egli L, Dussort P, Vinoy S, Rauh SP, Beulens JW, Robertson MD, Alssema M.

Eur J Nutr. 2021 Feb;60(1):259-273. doi: 10.1007/s00394-020-02240-1. Epub 2020 Apr 10. PMID: 32277270 Free PMC article.