1 A new framework for the diagnosis, staging and management of obesity in adults

Busetto L, Dicker D, Frühbeck G, Halford JCG, Sbraccia P, Yumuk V, Goossens GH

Nat Med. 2024 Jul 5. doi: 10.1038/s41591-024-03095-3. PMID: 38969880.


The impact of duration and severity of obesity exposure on cardiometabolic health

van Ede ES, Nienhuijs SW, Goossens GH, Bouwman RA, Buise MP.

Obes Surg. 2024 Jul;34(7):2587-2595. doi: 10.1007/s11695-024-07331-0. Epub 2024 Jun 4. PMID: 38833133; PMCID: PMC11217088.


3 Effects of early and late time-restricted feeding on parameters of metabolic health: an explorative literature assessment

Petridi F, Geurts JMW, Nyakayiru J, Schaafsma A, Schaafsma D, Meex RCR, Singh-Povel CM.

Nutrients. 2024. May 31;16(11):1721. doi: 10.3390/nu16111721. PMID: 38892654; PMCID: PMC11175017.


Fasting and postprandial plasma metabolite responses to a 12-week dietary intervention in tissue-specific insulin resistance: a secondary analysis of the PERSON randomized trial

Gijbels A, Jardon KM, Trouwborst I, Manusama KCM, Goossens GH, Blaak EE, Feskens EJM, Afman LA.  

Am J Clin Nutr. 2024 Jun 6:S0002-9165(24)00521-5. doi: 10.1016/j.ajcnut.2024.05.027. Epub ahead of print. PMID: 38851634.


Gut-bacteria derived membrane vesicles and host metabolic health: a narrative review

Verbunt J, Jocken J, Blaak E, Savelkoul P, Stassen F.  

Gut Microbes. 2024 Jan-Dec;16(1):2359515. doi: 10.1080/19490976.2024.2359515. Epub 2024 May 29. PMID: 38808455; PMCID: PMC11141482.


Immunometabolic Signatures of Circulating Monocytes in Humans with Obesity and Insulin Resistance

Smeehuijzen L, Gijbels A, Nugteren-Boogaard JP, Vrieling F, Boudjadja MB, Trouwborst I, Jardon KM, Hul GB, Feskens EJM, Blaak EE, Goossens GH, Afman LA, Stienstra R.  

Diabetes. 2024 Apr 24:db230970. doi: 10.2337/db23-0970. Epub ahead of print. PMID: 38656918.


7 Body composition and body fat distribution in tissue-specific insulin resistance and in response to a 12-week isocaloric dietary macronutrient intervention

Trouwborst I, Jardon KM, Gijbels A, Hul G, Feskens EJM, Afman LA, Linge J, Goossens GH, Blaak EE.  

Nutr Metab (Lond). 2024 Apr 9;21(1):20. doi: 10.1186/s12986-024-00795-y. PMID: 38594756; PMCID: PMC11003022.


Leveraging continuous glucose monitoring for personalized modeling of insulin-regulated glucose metabolism

Erdős B, O'Donovan SD, Adriaens ME, Gijbels A, Trouwborst I, Jardon KM, Goossens GH, Afman LA, Blaak EE, van Riel NAW, Arts ICW.

Sci Rep. 2024 Apr 5;14(1):8037. doi: 10.1038/s41598-024-58703-6. PMID: 38580749.


Hepatic insulin resistance and muscle insulin resistance are characterized by distinct postprandial plasma metabolite profiles: a cross-sectional study 

Gijbels A, Erdős B, Trouwborst I, Jardon KM, Adriaens ME, Goossens GH, Blaak EE, Feskens EJM, Afman LA

Cardiovasc Diabetol. 2024 Mar 16;23(1):97. doi: 10.1186/s12933-024-02188-0. PMID: 38493102; PMCID: PMC10944619.


10 Identification of circulating apolipoprotein M as a new determinant of insulin sensitivity and relationship with adiponectin

Frances L, Croyal M, Ruidavets JB, Maraninchi M, Combes G, Raffin J, de Souto Barreto P, Ferrières J, Blaak EE, Perret B, Moro C, Valéro R, Martinez LO, Viguerie N.

Int J Obes (Lond). 2024 Mar 15. doi: 10.1038/s41366-024-01510-w. Epub ahead of print. PMID: 38491190.


11 Sex differences in adipose insulin resistance are linked to obesity, lipolysis and insulin receptor substrate 1

Arner P, Viguerie N, Massier L, Rydén M, Astrup A, Blaak E, Langin D, Andersson DP.

Int J Obes (Lond). 2024 Mar 15. doi: 10.1038/s41366-024-01501-x. Epub ahead of print. PMID: 38491191.


12 The individual response to antibiotics and diet-insights into gut microbial resilience and host metabolism

Vliex LMM, Penders J, Nauta A, Zoetendal EG, Blaak EE

Nat Rev Endocrinol. 2024 Mar 14. doi: 10.1038/s41574-024-00966-0. Epub ahead of print. PMID: 38486011.


13 Fetuin B in white adipose tissue induces inflammation and its association with peripheral insulin resistance in mice and humans

Pasmans K, Goossens GH, Groenhuijzen E, Kemper EJ, Reijnders D, Most J, Blaak EEWatt MJ, Meex RCR.

Obesity (Silver Spring). 2024 Mar;32(3):517-527. doi: 10.1002/oby.23961. Epub 2023 Dec 19. PMID: 38112242.


14 Impaired mitochondrial respiration in upper compared to lower body differentiated human adipocytes and adipose tissue

Lempesis IG, Hoebers N, Essers Y, Jocken JWE, Dubois LJ, Blaak EE, Manolopoulos KN, Goossens GH.

J Clin Endocrinol Metab. 2024 Feb 20:dgae086. doi: 10.1210/clinem/dgae086. Epub ahead of print. PMID: 38375937.