Thesis Judith van Can

Modulation of fat oxidation

Nutritional and pharmacological approach

Obesity occurs more and more often, both in adults and in children. Obesity increases the risk of developing, for example, diabetes, high blood pressure and cardiovascular diseases. To raise the effectiveness of programmes that are aimed at body weight loss and the prevention of diabetes, extra strategies are necessary. This dissertation presents the effects of two nutrition strategies (changing the type of sugar in nutrition and the use of green tea supplements) and a pharmacological strategy that influence the fat oxidation. Although lifestyle intervention should be the first step in regulating body weight and prevention from diabetes, this approach does not appear effective for everyone. Food supplements or pharmacological interventions can be useful additions to make lifestyle interventions more successful.

Judith van Can, October 31th 2012